Publications

2026

Aneuploidy sensitizes cells to SREBP-pathway inhibition in squamous cell carcinoma
Zhakula-Kostadinova N, Jain S, Amini-Farsani Z, Zhang J, Nakamura M, Byron L, Castellano Perez JJ, Paolucci C, Munoth R, Zandkarimi F, Takemon Y, Marra M, Henick B, Saqi A, Reya T, Meyerson M, Taylor AM
bioRxiv, 2026
DOI | PubMed | Google Scholar

2025

Direct Injection Mass Spectrometry and iFishMass for the High-Throughput Analysis of Antibody Modifications
Aguilan J, Madrid-Aliste C, Zandkarimi F, Makarov A, Shoultz A, Ayesa U, Hu H, Dance ZEX, Saha-Shah A, Sidoli S
ACS Pharmacology & Translational Science, 9(1):165–176, 2025
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Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity
Reznik E, Zandkarimi F, Csuka JM, Zhu Q, Jin J, Neelakantan TV, Zheng J, Polychronidou V, Fongheiser M, Brown A, Qiu B, Rodriguez M, DeVine L, Subramaniam PS, Gu W, Califano A, Stockwell BR
Ferroptosis and Oxidative Stress, 1(1):202501, 2025
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Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry
Schebb NH, Kampschulte N, Hagn G, Plitzko K, Meckelmann SW, Ghosh S, Joshi R, Kuligowski J, Vuckovic D, Botana MT, Sánchez-Illana Á, Zandkarimi F, et al.
Science Signaling, 18(887):eadw1245, 2025
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Effects of the Quinone Analog Ubiquinone-5 on Murine Mitochondria and Hypnosis
Somnay YR, Wang A, Lim H, Griffiths KK, Zandkarimi F, Chen K, Yang G, Wasilczuk AZ, Kelz MB, Larr D, Yang M, Gil-Iturbe E, Moon A, Quick M, Levy RJ
Anesthesiology, 143(3):641–660, 2025
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Microneedle-mediated intracochlear injection safely achieves higher perilymphatic dexamethasone concentration than intratympanic delivery in guinea pig
Voruz F, Feng SJ, Breil E, Yu M, Hammer DR, Aksit A, Zandkarimi F, Olson ES, Kysar JW, Lalwani AK
Drug Delivery and Translational Research, 15(10):3595–3606, 2025
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Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma
Gallitto M, Zhang X, De Los Santos G, Wei HJ, Fernández EC, Duan S, Sedor G, Yoh N, Kokossis D, Angel JC, Wang YF, White E, Kinslow CJ, Berg X, Tomassoni L, Zandkarimi F, et al.
Neuro-Oncology, 27(3):795–810, 2025
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2024

Fatal COVID-19 pulmonary disease involves ferroptosis
Qiu B, Zandkarimi F, Saqi A, Castagna C, Tan H, Sekulic M, Miorin L, Hibshoosh H, Toyokuni S, Uchida K, Stockwell BR
Nature Communications, 15:3816, 2024
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OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
Liang FG, Zandkarimi F, Lee J, Axelrod JL, Pekson R, Yoon Y, Stockwell BR, Kitsis RN
Molecular Cell, 84(16):3098–3114.e6, 2024
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A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
Banu MA, Dovas A, Argenziano MG, Zhao W, Sperring CP, Cuervo Grajal H, Liu Z, Higgins DM, Amini M, Pereira B, Ye LF, Mahajan A, Humala N, Furnari JL, Upadhyayula PS, Zandkarimi F, et al.
The EMBO Journal, 43(20):4492–4521, 2024
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Evaluating the Ability of External Electric Fields to Accelerate Reactions in Solution
Aziz M, Prindle CR, Lee W, Zhang B, Schaack C, Steigerwald ML, Zandkarimi F, Nuckolls C, Venkataraman L
The Journal of Physical Chemistry B, 128(39):9553–9560, 2024
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Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury
Mann J, Reznik E, Santer M, Fongheiser MA, Smith N, Hirschhorn T, Zandkarimi F, Soni RK, Dafré AL, Miranda-Vizuete A, Farina M, Stockwell BR
Cell Chemical Biology, 31(2):249–264.e7, 2024
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2023

Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
Liang D, Feng Y, Zandkarimi F, Wang H, Zhang Z, Kim J, Cai Y, Gu W, Stockwell BR, Jiang X
Cell, 186(13):2748–2764.e22, 2023
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Identification of essential sites of lipid peroxidation in ferroptosis
von Krusenstiern AN, Robson RN, Qian N, Qiu B, Hu F, Reznik E, Smith N, Zandkarimi F, Estes VM, Dupont M, Hirschhorn T, Shchepinov MS, Min W, Woerpel KA, Stockwell BR
Nature Chemical Biology, 19(6):719–730, 2023
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Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism
Upadhyayula PS, Higgins DM, Mela A, Banu M, Dovas A, Zandkarimi F, Patel P, Mahajan A, Humala N, Nguyen TTT, Chaudhary KR, et al.
Nature Communications, 14:1187, 2023
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Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism
Yang X, Wang Z, Zandkarimi F, Liu Y, Duan S, Li Z, Kon N, Zhang Z, Jiang X, Stockwell BR, Gu W
Cell Metabolism, 35(8):1474–1490.e8, 2023
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DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids
Avard RC, Broad ML, Zandkarimi F, Devanny AJ, Hammer JL, Yu K, Guzman A, Kaufman LJ
Scientific Reports, 13(1):12383, 2023
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Red blood cell exposure increases chondrocyte susceptibility to oxidative stress following hemarthrosis
Lee AJ, Gangi LR, Zandkarimi F, Stockwell BR, Hung CT
Osteoarthritis and Cartilage, 31(10):1365–1376, 2023
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Comparison of the Cannabinoid and Terpene Profiles in Commercial Cannabis from Natural and Artificial Cultivation
Zandkarimi F, Decatur J, Casali J, Gordon T, Skibola C, Nuckolls C
Molecules, 28(2):833, 2023
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