APCI = Atmospheric Pressure Chemical Ionization | ASAP = Atmospheric Pressure Solids Analysis Probe | DESI = Desorption ElectroSpray Ionization | ESI = Electrospray Ionization | FIA = Flow Injection Analysis | MALDI = Matrix-Assisted Laser Desorption/Ionization | SFC = Supercritical Fluid Chromatography | TLC = Thin-Layer Chromatography | ToF = Time-of-Flight | TQ = Triple Quadrupole | UPLC = Ultra Performance Liquid Chromatography
High-resolution quadrupole time-of-flight (Q-ToF) LC-MS system for accurate mass measurements and MS/MS analysis using ESI and APCI ionization, coupled to a Waters H-Class UPLC. Supports intact protein and peptide analysis, small molecule characterization, and structural elucidation workflows. Located in 216 Havemeyer.
High-resolution quadrupole time-of-flight (Q-ToF) mass spectrometer with ion mobility separation (IMS) for confident structural characterization and isomer distinction. Supports untargeted metabolomics, lipidomics, and label-free mass spectrometry imaging (MSI) workflows. Coupled to a Waters DESI XS ion source for spatially resolved analysis of metabolites and lipids, and a Waters Acquity I-Class Plus UPLC for LC-MS analysis. Located in 216 Havemeyer.
High-resolution MALDI-TOF/TOF mass spectrometer for peptide, protein, glycoprotein, polymer, and small molecule analysis. Supports intact mass profiling, MS/MS-based structural characterization, and MALDI mass spectrometry imaging (MSI) workflows. Located in 216 Havemeyer.
Compact mass spectrometry system for routine molecular analysis and reaction monitoring in synthetic chemistry workflows. Equipped with a TLC plate reader for direct mass analysis of TLC spots. Supports rapid mass confirmation, purity assessment, and small molecule characterization. Located in 544 Havemeyer.
Supercritical fluid chromatography-mass spectrometry (SFC-MS) system for rapid small molecule analysis, chiral separations, and reaction monitoring in synthetic chemistry workflows. Supports compound characterization, purity assessment, and method development applications. Located in 544 Havemeyer.
* Additional column chemistries available including Torus DEA, Trefoil CEL2, and Viridis BEH 2-EP.
Triple quadrupole LC-MS/MS system for targeted quantitative analysis using MRM workflows. Designed for high-sensitivity detection and quantification of drugs, metabolites, lipids, and other small molecules in complex matrices. Located in 216 Havemeyer.